(+)-UH 232 Maleate is a selective modulator of dopamine receptor subtypes, acting as an endogenously preferential antagonist at D2 receptors and a partial agonist at D3 receptors. (+)-UH 232 Maleate selectively binds to and blocks D2 autoreceptors on central dopaminergic neurons, thereby lifting their negative feedback inhibition on dopamine synthesis and release. (+)-UH 232 Maleate binds to D3 receptors with low intrinsic activity (0.2-0.4) and can partially activate the receptor signaling pathway. (+)-UH 232 Maleate can be used for specific studies of dopaminergic nervous system function.
Molekulargewicht:
391.51
Reinheit:
99.67%
CAS Nummer:
[1217473-50-1]
Formel:
C22H33NO5
Target-Kategorie:
Dopamine Receptor
T23496L
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