Xestospongin C ((-)-Xestospongin C) is a selective inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor and also inhibits sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA). It has neuroprotective effects in APP/PS1 AD mice, improving cognitive and pathological deficits associated with Alzheimers disease.
Molekulargewicht:
446.71
CAS Nummer:
[88903-69-9]
Formel:
C28H50N2O2
Target-Kategorie:
Calcium Channel|||Apoptosis
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