CH5447240 is an effective Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist for the treatment of Hypoparathyroidism. CH5447240 showed a potent in vitro hPTHR1 agonist effect (EC20: 3.0 nM, EC50: 12 nM). It showed 55% oral bioavailability and a significantly elevated serum calcium level in hypocalcemic model rats.
Molekulargewicht:
517.68
CAS Nummer:
[1253919-92-4]
Formel:
C26H39N5O4S
Target-Kategorie:
Others|||Thyroid hormone receptor(THR)
T25234
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