L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
Molekulargewicht:
260.16
CAS Nummer:
[159190-45-1]
Formel:
C8H19Cl2N3O2
Target-Kategorie:
Others|||NO Synthase
T25749
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