Nolatrexed dihydrochloride, CAS [[152946-68-4]]

Artikelnummer: TGM-T2627
Artikelname: Nolatrexed dihydrochloride, CAS [[152946-68-4]]
Artikelnummer: TGM-T2627
Hersteller Artikelnummer: T2627
Alternativnummer: TGM-T2627-1MLX10MM(INDMSO),TGM-T2627-10MG,TGM-T2627-25MG,TGM-T2627-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Thymitaq , AG 337
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
Molekulargewicht: 357.26
Reinheit: 97.02%
CAS Nummer: [152946-68-4]
Formel: C14H14Cl2N4OS
Target-Kategorie: DNA/RNA Synthesis
T2627