Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
Molekulargewicht:
614.17
CAS Nummer:
[461023-63-2]
Formel:
C33H44ClN3O6
Target-Kategorie:
Others|||CCR|||HIV Protease
T26642
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