AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.
Molekulargewicht:
476.54
CAS Nummer:
[1383846-83-0]
Formel:
C30H25FN4O
Target-Kategorie:
Beta-Secretase|||Others
T26705
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