NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.50.35 µM.
Molekulargewicht:
367.42
CAS Nummer:
[1252802-38-2]
Formel:
C19H17N3O3S
Target-Kategorie:
Apoptosis|||Microtubule Associated|||Others
T28179
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