Dasminapant (SM-1387) is an inhibitor of apoptosis proteins antagonist that promotes rapid degradation of cIAP1/2 and XIAP, exhibiting pronounced antitumor effects against nasopharyngeal carcinoma stem cells and synergistically enhancing chemosensitivity and apoptosis when combined with cisplatin and 5-fluorouracil in both in vitro and in vivo models.
Molekulargewicht:
1157.41
CAS Nummer:
[1570231-89-8]
Formel:
C60H72N10O10S2
Target-Kategorie:
IAP
T30095
T30095
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