MK-571 sodium, CAS [[115103-85-0]]

Produktübersicht

• Artikelname: MK-571 sodium, CAS [[115103-85-0]]
• Artikelnummer: TGM-T3148
• Hersteller Artikelnummer: T3148
• Alternativnummer: TGM-T3148-1MLX10MM(INDMSO),TGM-T3148-2MG,TGM-T3148-5MG,TGM-T3148-10MG,TGM-T3148-25MG,TGM-T3148-50MG,TGM-T3148-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: MK571 sodium , L-660711 (sodium salt) , MK-571 sodium salt , Verlukast sodium , L-660711 sodium salt

Produktbeschreibung

MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the cellular efflux of drugs, xenobiotics, and their conjugates. MK-571 sodium can inhibit the synthesis of K-4'-O-GlcA (19.7 µM). MK571 dose-dependently inhibits the intracellular biosynthesis of all flavonol sulphates and glucuronides by Caco-2 cells. MK-571 sodium significantly inhibits phase-2 conjugation of kaempferol by cell-free extracts of Caco-2, and production of kaempferol-4'-O-glucuronide was competitively inhibited. In addition to inhibiting MRP2, MK571 is a potent inhibitor of enterocyte phase-2 conjugation.

Produkteigenschaften

• Molekulargewicht: 537.07
• Reinheit: 99.58%
• CAS Nummer: [115103-85-0]
• Formel: C26H27ClN2O3S2Na
• Target-Kategorie: LTR|||Leukotriene Receptor|||P-gp|||LPL Receptor

Bilder

T3148