Disoxaril (BRN 3626820, WIN 51711) is an anti-picornavirus agent that inhibits enterovirus replication by binding to a hydrophobic bag within the VP1 coat protein, thereby stabilizing virions and preventing their uncoating. When used in combination with Ambioxime and Bioxazole, there was a significant synergistic inhibition of poliovirus type 1 replication in FL cells.
Molekulargewicht:
342.43
CAS Nummer:
[87495-31-6]
Formel:
C20H26N2O3
Target-Kategorie:
Virus Protease|||Others
T31530
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