Halofuginone hydrobromide, CAS [[64924-67-0]]

Artikelnummer: TGM-T3524
Artikelname: Halofuginone hydrobromide, CAS [[64924-67-0]]
Artikelnummer: TGM-T3524
Hersteller Artikelnummer: T3524
Alternativnummer: TGM-T3524-1MLX10MM(INDMSO),TGM-T3524-1MG,TGM-T3524-2MG,TGM-T3524-5MG,TGM-T3524-10MG,TGM-T3524-25MG,TGM-T3524-50MG,TGM-T3524-100MG,TGM-T3524-500MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Tempostatin , RU-19110 (hydrobromide) , Stenorol
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases.
Molekulargewicht: 495.59
Reinheit: 97.01%
CAS Nummer: [64924-67-0]
Formel: C16H17BrClN3O3.HBr
Target-Kategorie: TGF-beta/Smad|||Sodium Channel|||Calcium Channel|||Parasite|||DNA/RNA Synthesis
T3524