Halofuginone hydrobromide, CAS [[64924-67-0]]
Artikelnummer:
TGM-T3524
- Bilder (1)
| Artikelname: | Halofuginone hydrobromide, CAS [[64924-67-0]] |
| Artikelnummer: | TGM-T3524 |
| Hersteller Artikelnummer: | T3524 |
| Alternativnummer: | TGM-T3524-1MLX10MM(INDMSO),TGM-T3524-1MG,TGM-T3524-2MG,TGM-T3524-5MG,TGM-T3524-10MG,TGM-T3524-25MG,TGM-T3524-50MG,TGM-T3524-100MG,TGM-T3524-500MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | Tempostatin , RU-19110 (hydrobromide) , Stenorol |
| Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases. |
| Molekulargewicht: | 495.59 |
| Reinheit: | 97.01% |
| CAS Nummer: | [64924-67-0] |
| Formel: | C16H17BrClN3O3.HBr |
| Target-Kategorie: | TGF-beta/Smad|||Sodium Channel|||Calcium Channel|||Parasite|||DNA/RNA Synthesis |

