Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption by promoting mucosal growth and reducing mucosal degradation, improving intestinal recovery. It is used in the study of short bowel syndrome (SBS). Teduglutide activates NR4a1/nur77 expression and FXR signaling, alleviating intestinal dysfunction in mice and improving lung injury, making it useful for studying metabolic and cardiovascular diseases.
Molekulargewicht:
3752.08
Reinheit:
98.08%
CAS Nummer:
[197922-42-2]
Formel:
C164H252N44O55S
Target-Kategorie:
FXR|||NR4A
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