Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with its ligands (PD-L1 and PL-L2).Sintilimab is used in combination with other compounds for the treatment of classical Hodgkins lymphoma, non-cellular lung cancer and esophageal cancer. Sintilimab is used in combination with other compounds to treat classical Hodgkins lymphoma, non-small cell lung cancer and esophageal cancer.
Reinheit:
95.00%
CAS Nummer:
[2072873-06-2]
Target-Kategorie:
PD-1/PD-L1
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