AC-4-130 is a direct STAT5 SH2 domain inhibitor that can disrupt STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent gene transcription, inducing cell cycle arrest and apoptosis in leukemia cells, and can be used for the study of acute myeloid leukemia (AML).
Molekulargewicht:
751.2
Reinheit:
99.93%
CAS Nummer:
[1834571-82-2]
Formel:
C37H36ClF5N2O5S
Target-Kategorie:
Cell Cycle Arrest|||Apoptosis|||STAT
T35429
T35429
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