(E)-5-(2-Bromovinyl)uracil, CAS [[69304-49-0]]

Produktübersicht

• Artikelname: (E)-5-(2-Bromovinyl)uracil, CAS [[69304-49-0]]
• Artikelnummer: TGM-T35439
• Hersteller Artikelnummer: T35439
• Alternativnummer: TGM-T35439-25MG,TGM-T35439-50MG,TGM-T35439-100MG,TGM-T35439-250MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2-deoxyuridine (BVDU), which can be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner, enhancing the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 µmol/kg, thereby increasing survival time.

Produkteigenschaften

• Molekulargewicht: 217.02
• CAS Nummer: [69304-49-0]
• Formel: C6H5BrN2O2
• Target-Kategorie: Others

Bilder

T35439