()14(15)-EET, CAS [[197508-62-6]]

Produktübersicht

• Artikelname: ()14(15)-EET, CAS [[197508-62-6]]
• Artikelnummer: TGM-T35463
• Hersteller Artikelnummer: T35463
• Alternativnummer: TGM-T35463-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: ()14,15-EET , ()14,15-EpETrE , ()14(15)-EET

Produktbeschreibung

()14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) induced by oxidized LDL in primary rat pulmonary artery endothelial cells (RPAECs) when used at a concentration of 1 µM.[3] ()14(15)-EET induces dilation of preconstricted isolated canine coronary arterioles (EC50 = 0.2 pM).[4] It reduces myocardial infarct size as a percentage of the area at risk in a canine model of ischemia-reperfusion injury induced by left anterior descending coronary artery (LAD) occlusion when administered at a dose of 0.128 mg/kg prior to occlusion or reperfusion.[5]

Produkteigenschaften

• Molekulargewicht: 320.473
• CAS Nummer: [197508-62-6]
• Formel: C20H32O3
• Target-Kategorie: Others

Bilder

T35463