HPI-1 (hydrate), CAS [[1262770-72-8]]

Produktübersicht

• Artikelname: HPI-1 (hydrate), CAS [[1262770-72-8]]
• Artikelnummer: TGM-T35538
• Hersteller Artikelnummer: T35538
• Alternativnummer: TGM-T35538-25MG,TGM-T35538-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: HPI-1 hydrate

Produktbeschreibung

HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 µM) without significantly affecting Wnt signaling (IC50 30 µM).1HPI-1 suppresses Hh activation induced by loss of Suppressor of Fused or by Gli overexpression, suggesting action at posttranslational modification of Gli protein or at the interaction of Gli with a co-factor.1HPI-1 (hydrate) also inhibits signaling through the oncogenic Smoothened (Smo) mutant SmoM2 in neuron precursors, preventing cell proliferation.1

Produkteigenschaften

• Molekulargewicht: 481.54
• CAS Nummer: [1262770-72-8]
• Formel: C27H31NO7
• Target-Kategorie: Others

Bilder

T35538