Desmethylanethol trithione, CAS [[18274-81-2]]

Produktübersicht

• Artikelname: Desmethylanethol trithione, CAS [[18274-81-2]]
• Artikelnummer: TGM-T3560
• Hersteller Artikelnummer: T3560
• Alternativnummer: TGM-T3560-1MLX10MM(INDMSO),TGM-T3560-10MG,TGM-T3560-25MG,TGM-T3560-50MG,TGM-T3560-100MG,TGM-T3560-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: ADT-OH

Produktbeschreibung

Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly attenuated tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Finally, Desmethylanethol trithione improved functional outcomes in mice subjected to MCAO and tPA infusion. H2S donors reduced tPA-induced cerebral hemorrhage by possibly inhibiting the Akt-VEGF-MMP9 cascade. Administration of H2S donors has potential as a novel modality to improve the safety of tPA following the stroke.

Produkteigenschaften

• Molekulargewicht: 226.34
• Reinheit: 98.41%
• CAS Nummer: [18274-81-2]
• Formel: C9H6OS3
• Target-Kategorie: VEGFR|||FAK|||Apoptosis|||Akt

Bilder

T3560