Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 µM). Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells. It also has antibiotic and antifungal actions.
Molekulargewicht:
1129.385
CAS Nummer:
[194874-06-1]
Formel:
C58H96O21
Target-Kategorie:
Others|||ATPase|||Apoptosis
T35605
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