Cytostatin (sodium salt), CAS [[457070-06-3]] Preis auf Anfrage
Artikelnummer:
TGM-T35613
Hersteller Artikelnummer:
T35613
Alternativnummer:
TGM-T35613-1MG,TGM-T35613-250UG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Cytostatin (sodium salt) is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 µg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 µg/ml). Cytostatin (sodium salt) potently and selectively inhibits protein phosphatase 2A (PP2A, IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
Molekulargewicht:
451.452
CAS Nummer:
[457070-06-3]
Formel:
C21H33NaO7P
Target-Kategorie:
Others|||Apoptosis|||Phosphatase
T35613
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