Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.
Molekulargewicht:
184.2
Reinheit:
98.00%
CAS Nummer:
[459-86-9]
Formel:
C5H12N8
Target-Kategorie:
Apoptosis|||HIV Protease
T35617
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