Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1.56-12.5 µg/ml).1Napyradiomycin A1is an estrogen receptor antagonist (IC50= 4.2 µM in rat uterine homogenates).2It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 µM, respectively).3
Molekulargewicht:
481.41
CAS Nummer:
[103106-24-7]
Formel:
C25H30Cl2O5
Target-Kategorie:
Antibacterial|||Others|||Antibiotic
T35667
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