Myxochelin A is a microbial metabolite found in *A. disciformis* with diverse biological activities. It exhibits activity against Gram-positive bacteria, including *B. cereus*, *S. aureus*, and *M. luteus*, but not against Gram-negative bacteria or fungi at a concentration of 80 µg/disc in an agar diffusion assay. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity, with an IC50 value of 1.9 µM for the recombinant human enzyme. Additionally, it is cytotoxic to 26-L5 colon cancer cells at a concentration of 3 µg/ml.
Molekulargewicht:
404.419
CAS Nummer:
[120243-02-9]
Formel:
C20H24N2O7
Target-Kategorie:
Others|||Lipoxygenase
T35692
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