Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulates inflammatory responses, scoured 2, 2-diphenyl-1-PicrylHydrazyl radicals in a cell-free assay (IC50 = 2.4 µg/ml), In the oxygen radical absorption capacity (ORAC) test at concentrations of 1.6 to 6.4 µg/ml, Its Trolox value was 2.6. Thymus hydroquinone inhibited the growth of A2780, OVCAR-8 and CIS-A2780 ovarian cancer cells (IC50 were 3.1, 8.9 and 9.8 µM, respectively) and human ovarian immortalized epithelial cells (IC50 = 14 µM). It also inhibited Plasmodium falciparum in vitro (IC50 = 15.9 µM).
Molekulargewicht:
166.22
Reinheit:
99.60%
CAS Nummer:
[2217-60-9]
Formel:
C10H14O2
Target-Kategorie:
Reactive Oxygen Species|||Antioxidant|||ROS
T35749
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