Swinholide A is a polyketone compound that can be extracted from sponges and binds to actin to dimerize actin with Kd of about 50 nM. Swinholide A is a cytotoxin that stabilizes actin dimers and severs actin filaments. Swinholide A has antifungal activity and can damage the actin cytoskeleton of cells.
Molekulargewicht:
1389.87
CAS Nummer:
[95927-67-6]
Formel:
C78H132O20
Target-Kategorie:
Antifungal
T35782
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