Trichostatin C is a glycosylated derivative of trichostatin A , the antifungal antibiotic that reversibly inhibits histone deacetylase. Trichostatin C is reported to be the first example of a glucopyranosyl hydroxamate identified in nature. It has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A.
Molekulargewicht:
464.515
CAS Nummer:
[68676-88-0]
Formel:
C23H32N2O8
Target-Kategorie:
Apoptosis|||Others|||HDAC|||Antifungal
T35825
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