Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities, showing selective and potent antimicrobial activity against H. pylori (MIC = 0.1 ng/mL) and no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis. It mildly inhibits the growth of Gram-positive bacteria and dermatophytes with MIC values ranging from <6.25 to 25 µg/mL. Intravenous administration of actinopyrone A (30 µg/kg) increases coronary blood flow in dogs by 196.2%.
Molekulargewicht:
400.559
CAS Nummer:
[88378-59-0]
Formel:
C25H36O4
Target-Kategorie:
Others
T35857
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