BRD-8000.3 is a narrow-spectrum, bactericidal antimycobacterial agent that specifically inhibits EfpA,specifically designed to kill drug-tolerant Mtb.Study revealed BRD-8000.3 at resolutions of 2.9 A and 3.4 A, resp, EfpA forms an antiparallel dimer. Functional studies reveal that EfpA is a lipid transporter and BRD-8000.3 inhibits its lipid transport activity.
Molekulargewicht:
401.3
Reinheit:
99.78%
CAS Nummer:
[2365504-95-4]
Formel:
C19H21BrN4O
Target-Kategorie:
Antibiotic
T35872
T35872
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