4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized omega-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of omega-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other omega-6 fatty acids, particularly arachidonic acid.
Molekulargewicht:
172.224
CAS Nummer:
[7439-43-2]
Formel:
C9H16O3
Target-Kategorie:
Others|||Reactive Oxygen Species
T36001
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