17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when used at concentrations ranging from 0.1 to 10 nM. 17(R)-Protectin D1 (0.01-10 ng) reduces the recruitment of neutrophils in a mouse model of TNF-alpha-induced peritonitis.
Molekulargewicht:
360.49
CAS Nummer:
[1365694-03-6]
Formel:
C22H32O4
Target-Kategorie:
Others
T36043
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