BMP-22, CAS [[1306684-90-1]]

Produktübersicht

• Artikelname: BMP-22, CAS [[1306684-90-1]]
• Artikelnummer: TGM-T36138
• Hersteller Artikelnummer: T36138
• Alternativnummer: TGM-T36138-1MG,TGM-T36138-5MG,TGM-T36138-10MG,TGM-T36138-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 µM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine in vitro in a concentration-dependent manner. It inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 (0.5 mg/kg per day) decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis.

Produkteigenschaften

• Molekulargewicht: 382.52
• CAS Nummer: [1306684-90-1]
• Formel: C22H39O3P
• Target-Kategorie: Others|||PDE

Bilder

T36138