14,15-EE-5(Z)-E, CAS [[519038-92-7]]

Artikelnummer: TGM-T36150
Artikelname: 14,15-EE-5(Z)-E, CAS [[519038-92-7]]
Artikelnummer: TGM-T36150
Hersteller Artikelnummer: T36150
Alternativnummer: TGM-T36150-25UG,TGM-T36150-50UG,TGM-T36150-100UG,TGM-T36150-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Molekulargewicht: 324.505
CAS Nummer: [519038-92-7]
Formel: C20H36O3
Target-Kategorie: Others|||Endogenous Metabolite
T36150