8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha, CAS [[191919-02-5]]

Produktübersicht

• Artikelname: 8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha, CAS [[191919-02-5]]
• Artikelnummer: TGM-T36165
• Hersteller Artikelnummer: T36165
• Alternativnummer: TGM-T36165-1MG,TGM-T36165-100UG,TGM-T36165-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: 8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha

Produktbeschreibung

8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha (8-iso-13,14-dihydro-15-keto PGF2alpha) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2alpha), in rabbits, monkeys and humans. 8-iso PGF2alpha is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by beta-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into rabbits. Early in the infusion (within 10 minutes) 8-iso-13,14-dihydro-15-keto PGF2alpha was a significant component of the metabolite profile, which was comprised mostly of dinor 8-isoprostane metabolites. 8-iso-13,14-dihydro-15-keto PGF2alpha weakly inhibits the U-46619 or collagen-induced aggregation of human platelets, although a number of the E-series isoprostanes are much more potent in this assay.

Produkteigenschaften

• Molekulargewicht: 354.48
• CAS Nummer: [191919-02-5]
• Formel: C20H34O5
• Target-Kategorie: Others|||Endogenous Metabolite

Bilder

T36165