AZD5582 dihydrochloride, CAS [[1883545-51-4]]

Produktübersicht

• Artikelname: AZD5582 dihydrochloride, CAS [[1883545-51-4]]
• Artikelnummer: TGM-T36201
• Hersteller Artikelnummer: T36201
• Alternativnummer: TGM-T36201-10MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: AZD 5582 dihydrochloride

Produktbeschreibung

Dimeric Smac mimetic, potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.

Produkteigenschaften

• Molekulargewicht: 1088.23
• CAS Nummer: [1883545-51-4]
• Formel: C58H80Cl2N8O8
• Target-Kategorie: Others|||Apoptosis|||IAP

Bilder

T36201