Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 µM, as well as inhibits cholesterol synthesis (IC50= 0.78 µM), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 µM).2
Molekulargewicht:
487.63
CAS Nummer:
[154491-55-1]
Formel:
C27H41N3O5
Target-Kategorie:
Others|||Endogenous Metabolite
T36226
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