Arecaidine propargyl ester (hydrobromide), CAS [[116511-28-5]]

Produktübersicht

• Artikelname: Arecaidine propargyl ester (hydrobromide), CAS [[116511-28-5]]
• Artikelnummer: TGM-T36241
• Hersteller Artikelnummer: T36241
• Alternativnummer: TGM-T36241-5MG,TGM-T36241-10MG,TGM-T36241-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 µM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 µM.2Arecaidine propargyl ester decreases mean arterial blood pressure in normotensive cats (ED25= 1.9 nmol/kg).3It is toxic to house flies (Musca) when administered at a dose of 75 µg/fly.4

Produkteigenschaften

• Molekulargewicht: 260.13
• CAS Nummer: [116511-28-5]
• Formel: C10H14BrNO2
• Target-Kategorie: Others|||Apoptosis

Bilder

T36241