LC-2, CAS [[2502156-03-6]]

Produktübersicht

• Artikelname: LC-2, CAS [[2502156-03-6]]
• Artikelnummer: TGM-T36256
• Hersteller Artikelnummer: T36256
• Alternativnummer: TGM-T36256-1MG,TGM-T36256-5MG,TGM-T36256-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: PROTAC KRASG12C Degrader-LC-2 , LC 2 , LC2

Produktbeschreibung

LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 µM.LC-2 is a PROTAC that covalently binds KRAS G12C with MRTX849 and recruits the E3 ligase, VH, to induce a rapid and sustained degradation of KRAS G12C. LC-2 inhibits MAPK signaling in pure and heterozygous KRAS G12C cell lines.

Produkteigenschaften

• Molekulargewicht: 1132.78
• Reinheit: 98.00%
• CAS Nummer: [2502156-03-6]
• Formel: C59H71ClFN11O7S
• Target-Kategorie: Kras|||PROTACs|||Ras

Bilder

T36256