Acalabrutinib, CAS [[1420477-60-6]]

Produktübersicht

• Artikelname: Acalabrutinib, CAS [[1420477-60-6]]
• Artikelnummer: TGM-T3626
• Hersteller Artikelnummer: T3626
• Alternativnummer: TGM-T3626-1MLX10MM(INDMSO),TGM-T3626-5MG,TGM-T3626-10MG,TGM-T3626-25MG,TGM-T3626-50MG,TGM-T3626-100MG,TGM-T3626-200MG,TGM-T3626-500MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: ACP-196

Produktbeschreibung

Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Brutons tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies, it plays an important role in B lymphocyte development, activation, signaling, proliferation and survival.

Produkteigenschaften

• Molekulargewicht: 465.51
• Reinheit: 98.94%
• CAS Nummer: [1420477-60-6]
• Formel: C26H23N7O2
• Target-Kategorie: BTK

Bilder

T3626