Cho-Arg (trifluoroacetate salt), CAS [[1609010-56-1]]
Artikelnummer:
TGM-T36350
Hersteller Artikelnummer:
T36350
Alternativnummer:
TGM-T36350-1MG,TGM-T36350-5MG,TGM-T36350-10MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-beta-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 µg/ml).
Molekulargewicht:
884.059
CAS Nummer:
[1609010-56-1]
Formel:
C43H71F6N5O7
Target-Kategorie:
Others|||Liposome
T36350
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