Paclitaxel octadecanedioate, CAS [[2089211-45-8]]

Produktübersicht

• Artikelname: Paclitaxel octadecanedioate, CAS [[2089211-45-8]]
• Artikelnummer: TGM-T36398
• Hersteller Artikelnummer: T36398
• Alternativnummer: TGM-T36398-1MG,TGM-T36398-5MG,TGM-T36398-10MG,TGM-T36398-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 µM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft model in a dose-dependent manner.

Produkteigenschaften

• Molekulargewicht: 1150.369
• CAS Nummer: [2089211-45-8]
• Formel: C65H83NO17
• Target-Kategorie: Others

Bilder

T36398