(3S)-hydroxy Quinidine, CAS [[53467-23-5]]

Produktübersicht

• Artikelname: (3S)-hydroxy Quinidine, CAS [[53467-23-5]]
• Artikelnummer: TGM-T36561
• Hersteller Artikelnummer: T36561
• Alternativnummer: TGM-T36561-1MG,TGM-T36561-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.

Produkteigenschaften

• Molekulargewicht: 340.42
• CAS Nummer: [53467-23-5]
• Formel: C20H24N2O3
• Target-Kategorie: Others|||Drug Metabolite

Bilder

T36561