12(S)-HETrE, CAS [[72710-10-2]]

Produktübersicht

• Artikelname: 12(S)-HETrE, CAS [[72710-10-2]]
• Artikelnummer: TGM-T36773
• Hersteller Artikelnummer: T36773
• Alternativnummer: TGM-T36773-25UG,TGM-T36773-50UG,TGM-T36773-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

12(S)-HETrE is an endogenous metabolite produced by oxidation of omega-6 PUFA dihomo-gamma-linolenic acid (DGLA) by 12-lipoxygenase (12-LOX) in platelets, which acts on Galphas-coupled G-protein-coupled receptors, has antithrombotic properties, and has potential therapeutic use in cardiovascular disease. 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), alpha granule secretion, integrin alphaIIbbeta3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.

Produkteigenschaften

• Molekulargewicht: 322.48
• CAS Nummer: [72710-10-2]
• Formel: C20H34O3
• Target-Kategorie: Others|||PKA|||Integrin|||Endogenous Metabolite

Bilder

T36773

T36773