(R)-Bromoenol lactone, CAS [[478288-90-3]]

Produktübersicht

• Artikelname: (R)-Bromoenol lactone, CAS [[478288-90-3]]
• Artikelnummer: TGM-T36838
• Hersteller Artikelnummer: T36838
• Alternativnummer: TGM-T36838-1MG,TGM-T36838-5MG,TGM-T36838-10MG,TGM-T36838-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase gamma (iPLA2gamma). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2beta except at high doses of 20-30 µM. (R)-BEL inhibits human recombinant iPLA2gamma with an IC50 of approximately 0.6 µM.

Produkteigenschaften

• Molekulargewicht: 317.18
• CAS Nummer: [478288-90-3]
• Formel: C16H13BrO2
• Target-Kategorie: Phospholipase|||Others

Bilder

T36838