Inostamycin A, a bacterial metabolite isolated from Streptomyces with antimicrobial and anticancer activity, is a selective inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase, thereby blocking the phosphatidylinositol turnover.Inostamycin A induces apoptosis in cancer cells and exhibits concentration-dependent cytotoxicity in a variety of cancer cell lines.
Molekulargewicht:
700.94
CAS Nummer:
[129905-10-8]
Formel:
C38H68O11
Target-Kategorie:
Endogenous Metabolite
T36844
T36844
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