SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50= 6.7 µM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50= 5.33 µM) but not cathepsin B when used at a concentration of 20 µM.
Molekulargewicht:
199.3
CAS Nummer:
[433212-75-0]
Formel:
C7H9N3S2
Target-Kategorie:
Others|||Cysteine Protease|||SARS-CoV
T36942
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