Ara-G is a deoxyguanosine (GdR) analog and a nucleoside analogue that is rapidly converted by cells of the T lymphoid lineage to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and selective in vitro toxicity to T lymphoblastoid cell lines as well as to freshly isolated leukemia cells from patients with T cell acute lymphoblastic leukemia (ALL).
Molekulargewicht:
283.24
Reinheit:
99.93%
CAS Nummer:
[38819-10-2]
Formel:
C10H13N5O5
Target-Kategorie:
Nucleoside Antimetabolite/Analog|||Others
T36944
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