MRT 67307 dihydrochloride is a dual inhibitor of the IKKepsilon and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 dihydrochloride also blocks autophagy in cells.
Molekulargewicht:
537.53
Reinheit:
98.43%
CAS Nummer:
[1781882-89-0]
Formel:
C26H38Cl2N6O2
Target-Kategorie:
Autophagy|||SIK|||IkappaB/IKK
T36994
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