hnRNPK-IN-1 is a specific ligand that binds to the heterogeneous nuclear ribonucleoprotein K (hnRNPK) with high affinity, evidenced by Kd values of 4.6 µM and 2.6 µM determined using surface plasmon resonance (SPR) and microscale thermophoresis (MST), respectively. This binding event leads to the disruption of hnRNPKs interaction with the c-myc promoter, resulting in the inhibition of c-myc transcription. Additionally, hnRNPK-IN-1 induces apoptosis in Hela cells and exhibits potent anti-tumor activities[1].
Molekulargewicht:
419.43
CAS Nummer:
[2313528-04-8]
Formel:
C23H21N3O5
Target-Kategorie:
Others|||Apoptosis|||c-Myc
T37036
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