TL13-22 is a potent inhibitor of Anaplastic Lymphoma Kinase (ALK) with an IC50 value of 0.54 nM and does not lead to degradation of ALK proteins.TL13-22 is often used as a negative control for TL13-12 (induces ALK protein degradation) as a negative control.TL13-22 also induces degradation of other kinases, including Aurora A, FER, PTK2, and RPS6KA1.
Molekulargewicht:
947.5
Reinheit:
99.13%
CAS Nummer:
[2229036-65-9]
Formel:
C45H55ClN10O9S
Target-Kategorie:
ALK
T37084
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